Nature microbiology
Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection
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Our science addresses an extensive array of subjects, from the fundamental question of why and how WARS1 is secreted to regulate the immune system to the creation of ground-breaking innovative medications to control patients’ aberrant WARS1 activity.
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Experimental & Molecular Medicine
Immunopathology of and potential therapeutics for secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome: a translational perspective
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EMBO Molecular Medicine
Highly secreted tryptophanyl-tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis
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SHOCK
Secreted tryptophanyl-tRNA synthetase 1 is a prognostic markerin sepsis patients without monocytopenia
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CELL REPORTS
Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
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Biomolecules
Tryptophanyl-tRNA synthetase 1 signals activate TREM-1 via TLR2 and TLR4
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Experimental & Molecular Medicine
Unique roles of tryptophanyl-tRNA synthetase in immune control and its therapeutic implications
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